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Moreover, air pollution, particularly extended exposure to fine particulate matter such as PM2.5, correlates with an increased risk of diabetes onset and challenges in blood sugar regulation

10.3389/fnmol.2016.00030 Front

According to Ansari et al

They suppress neuronal necroptosis by disrupting the receptor-interacting protein kinase 1 (RIPK1)-RIPK3 interaction and mitigate ferroptosis via the delivery of miR-218a-5p, which triggers a cascade involving B cell-specific Moloney murine leukemia virus integration site 1 (Bmi1)-mediated methyltransferase-like 3 (Mettl 3) degradation, a reduction in ribosomal protein S6 kinase beta-1 (p70S6K) mRNA, and ultimately, decreased lipid peroxidation (77)