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The multifaceted role of mitochondria in -cells encompasses pivotal processes and pathways, including mitochondrial bioenergetics and metabolism, proton leak, calcium (Ca 2+ ), structural integrity, dynamics, as well as turnover/mitophagy

Rivard A, Fabre JE, Silver M, Chen D, Murohara T, Kearney M, Magner M, Asahara T, Isner JM (1999) Age-dependent impairment of angiogenesis

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Clinically reportable genetic changes can frequently be found in patients with apparently sporadic disease

Measurement of TNF- levels in the supernatants recovered from NAC-treated granulomas at 8 and 15 days indicated a two and three-fold decrease, respectively in the production of this cytokine (Figures 2G,H)