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The pes anserine bursa sits two to three inches below the inner joint line, where three tendons attach to the shinbone

10.1016/j.steroids.2012.03.011 40

[2] For example, 2 healthy adults and 1 child need (1 gallon or 3.8 liters / adult) x (2 adults) + (1.5 gal or 5.7 liters / child) x (1 child) = 3.5 gallons (13.25 liters) per day

It's been shown to improve healing of intestinal anastomoses, which is the surgical reconnection of bowel after part of it is removed

This retention advantage may explain why some patients feel more prolonged effects from methylcobalamin even if blood levels look similar

References Paediatric Gastroenterology Clinical Network