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Immunoreactivity may decrease in some cases of immunostaining when samples are fixed in paraffin blocks and stored at room temperature, compared to when they are stored under cold conditions [30]

Garrett, L.J.A., Revell, S.G

Such properties are responsible for their potency against voltage-gated ion channels, G-protein-coupled receptors and neurotransmitter transporters, making them attractive leads for drug development 6

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It means that an oral capsule can survive the journey to the intestines and be absorbed systemically, exerting its influence throughout the body