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43 Serum homocysteine is less specific for B 12 deficiency, and can also be elevated in folate deficiency, vitamin B 6 deficiency, vitamin B 2 deficiency, and impaired renal function, hypothyroidism, and by certain medications

Although vitamin B12 and the terms used interchangeably

Evidence from observational studies suggests that with longer symptom duration and more profound B 12 deficiency, the likelihood that neurological symptoms will not completely resolve increases

Certain B vitamins, including B12 and folate, benefit gut health by supporting the growth of beneficial bacteria

Sometimes a surgeon will determine that the risks of remaining on these drugs are too significant and collaborate with the patient to develop a safer approach

New or unexpected symptoms : Whilst rare, allergic reactions to hydroxocobalamin can occur