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the invention contemplates the use of antisense, siRNA, and other nucleic acids in which a portion of the linkages are replaced with, for example, the neutral methyl phosphonate or phosphoramidate linkages

Areca nut alkaloids induce irreparable DNA damage and senescence in fibroblasts and may create a favourable environment for tumour progression

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By contrast, untreated controls showed a 39% increase in homocysteine levels, suggesting that homocysteine levels can be sustained with long-term CDX-6512 treatment (46)

Neurology 45 , 16781683 (1995)