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[DOI] [PMC free article] [PubMed] [Google Scholar] 72.Hanolu A., Karaolu M.M., Bedir Y

Advanced Dermal Remodeling Investigated for its ability to reverse the gene signature of aging skin

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This treatment was originally performed with local anesthetic and dextrose, but further research has shown increased benefits with other agents

GHK-Cu research, meanwhile, documents upregulation of collagen synthesis genes and matrix metalloproteinase regulation, both pathways relevant to cartilage maintenance and repair research