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To ensure that the compounds identified in our parent and pDC-based assays were specific inhibitors of the interaction between STX7 and Munc13-4 but did not interfere with vesicle docking and exocytosis by inhibiting RabsMunc13-4 complexes, ENDO compounds were counterscreened in TR-FRET assays using lysates expressing FlagMunc13-4 and EGFPRab27a or EGFPRab11

Studied for oxidative stress, detoxification, and skin research models

performed the behavioral and molecular experiments in rats with input from L.T

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GSH-activated prodrugs, including disulfide- and diselenide-linked conjugates, are selectively activated in tumors, enabling high drug loading and targeted delivery

Surrounded by limestone mountain ranges with many caves, the lake features two small islands, An M Island and B Ga Island