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This proof-of-principle study highlights the therapeutic potential of CRISPRa in reducing the incidence of spontaneous seizures in vivo

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In plants, ferroptosis-like cell death has been reported in Arabidopsis root hairs subjected to 55 C heat shock (Distfano et al

Most native proteins have marginally stable folding patterns, and the accumulation of misfolded proteins can disrupt intracellular protein homeostasis networks, thereby inducing various diseases [13]

In particular, core symptoms (extenuating fatigue, cognitive problems, sleep disorders and pain) not only strengthen but often exacerbate each other, leading to isolation, depression, and sometimes even to a state that looks like PTSD