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Elevated hematocrit means a higher concentration of red blood cells, which can lead to incre

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Dysfunction of the ETC, such as deficiencies in Complex III or V, leads to fatty acid accumulation and reduced histone acetylation levels, ultimately impeding hepatocyte proliferation [151]

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Patients with sufficient vitamin D had lower MMP1 and MMP13 levels compared to those with insufficiency of vitamin D, suggesting that vitamin D promotes anti-resorption by upregulating antioxidant enzymes like PON-1 and TAC and downregulating MMPs like MMP1 and MMP13, to protect against cartilage degradation in OA