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Another in vitro EAAT2-inducing compound, MS-153, effectively protected against secondary neurodegeneration after traumatic brain injury, but through mechanisms other that EAAT2 upregulation (Fontana et al., As described in the Section on The Concepts of Acute and Chronic Glutamate Toxicity, Glud1 Tg mice represent a model of chronic excitotoxicity mediated by increased synaptic L-glu release with limited neuronal loss (Bao et al., 1997

The use of PMA prior to DNA extraction and subsequent qPCR analysis significantly enhanced the accuracy of microbial abundance measurements by selectively eliminating DNA originating from non-viable cells