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J Inherit Metab Dis 2012;35:679-87

However, the iron available from PIC is absorbed in the lower gut, via an active protein transport mechanism"

Sicard, F., Vogeleer, P., Bihan, G

Comparative Effects of Herbicide Dicamba and Related Compound on Plant Mitochondrial Bioenergetics

This route is particularly relevant for gastrointestinal applications

Charge-reversible nanoparticles can modify their surface charge in response to pH fluctuations, thereby improving cellular uptake in tumors via electrostatic interactions with the negatively charged cell membrane (99, 100)