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Further mechanistic investigations revealed that hepatic DRP1 deficiency led to increased mtDNA levels and mitochondrial dysfunction, resulting in the activation of the cGAS-STING-interferon signaling pathway and exacerbating alcohol-induced liver injury

Wiese, Jeff, et al

Acute inflammatory activity of microglia and infiltrated macrophages causes an oxidative burst, but chronic low-grade microglia/astrocyte activation is also a frequent characteristic of neurological disease

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Therefore, the discovery of healthy and effective management options for IBD is crucial

Formulation, optimization and evaluation of piperine loaded nanovesicles medicated drug delivery for the treatment of cancer