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doi: 10.1016/j.autrev.2023.103428 236 KaoAHNavratilJSRuffingMJLiuCCHawkinsDMcKinnonKMet al

The nuclear translocation of -syn increases susceptibility of MES23.5 cells to oxidative stress (Zhou et al., 2013)

Kavanagh JJ, Spriggs D, Bookman M, Ozols R, Gershenson DM, Han J, Lewis L, Brown GL, Dombrowski J, Maack C, Macpherson J, Lane A, Woodrow P and Henner WD

3.1.3 Enzymes, surface molecules and antioxidant systems After SCI, microglia switch on the NLRP3-caspase-1GSDMD axis, causing pyroptotic rupture and a surge of IL-1/IL-18 that fuels secondary tissue loss