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doi: 10.1136/ard-2023-223929 165 MikulsTRPayneJBYuFThieleGMReynoldsRJCannonGWet al

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Iron, ferroptosis and lipid redox homeodynamics We can measure the labile iron pool (LIP) in cells, but spatiotemporal LIP mapping in vivoincluding ferritinophagy pulses, heme turnover and mitochondrialysosome exchangeremains rudimentary

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In accord with the behavior of autophagy inhibitors, apoE lost potency after long exposures (48 h) and after high doses of erastin (Fig