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However, their therapeutic index is often narrowas exemplified by deferoxamine, which, despite being well-studied, is currently limited to treating acute iron poisoning and conditions involving chronic blood transfusions (e.g., thalassemia)

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Reference: Michiels C et al

If they are fat soluble, theyre getting deposited in the body

However, many people still develop deficiencies due to diet, absorption issues, or lifestyle factors

doi: 10.1038/nrd.2018.149 61 MarquezA.GuernseyL