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These observations support the theory that mitochondrial dysfunction and ATP reduction are among the first changes that occur following IOP elevation and may be maintained

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After treatment with MV, the cells were washed with ice-cold PBS for 3 times, and fixed with 4% paraformaldehyde in PBS

In phi and tau GST enzymes, the active site, characterized by the presence of a conserved serine residue, activates the sulfur atom in the cysteine residue in GSH (i.e., lowers its pKa), forming reactive thiolate species (Cummins et al