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doi: 10.1016/j.pnpbp.2015.02.009

Mechanistically, Vitamin D 3 acts through multiple pathways in psoriasis ( Figure 3A ) ( Table 3 ): regulating keratinocyte growth and differentiation (87), enhancing antimicrobial barrier function through LL-37 induction (88), suppressing pathogenic Th1/Th17 responses while promoting Tregs (89), and inhibiting DCs and macrophage activation (90)

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Indeed, breathing 100% oxygen at a pressure of 2 ATA increases the oxygen diffusion radius up to more than 4-fold

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