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178 Meanwhile, arginine deprivation promotes GCN2-dependent cycle arrest in HCC cells, and inhibition of GCN2 in arginine-deprived HCC cells promotes cellular senescence and increases the efficacy of senolytic compounds (Fig

[DOI] [PMC free article] [PubMed] [Google Scholar] 167.Hasegawa T., Mikoda N., Kitazawa M., LaFerla F.M

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For C677T, the enzyme activity of heterozygous and homozygous mutant individuals are respectively 67 and 25% of the wild-type ones

Also, studies have reported high levels of oxidation products of linoleic acid in patients with early cataract (Figure 1

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