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While this disagreement on anti-band 3 specificity continued (Kay et al., 1988

Castanedo-Cazares et al

Phase 3 TRIUMPH-4 showed 28.7% weight loss at 68 weeks, substantially exceeding CagriSema's 20.4% at 68 weeks

As these were already lower in the mutants compared to the WT this led to stronger phenotypes regarding root length and total biomass production

For example, the redox activitiy of p66Shc within mitochondria has been shown to generate H 2 O 2 in the absence of superoxide through oxidation of cytochrome c ( 2 O 2