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GSH and combined treatment primarily reduced their levels, while meropenem led to a slight increase (Figure 6B)

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Interestingly, the administration of SP, L-car, and their combination was able to reverse the changes in hormonal levels as presented in the DOX + SP, DOX + L-car, and DOX+(SP + L-car) groups, especially the DOX+(SP + L-car), unlike the DOX group, reflecting their protective role against ovarian toxicity induced by DOX

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10.1016/j.redox.2018.05.002 131 RaiG.MishraS.SumanS.ShuklaY