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Neuronal and glial alterations, increased anxiety, and cognitive impairment before hippocampal amyloid deposition in PDAPP mice, model of Alzheimers disease

journals.sagepub.com/doi/full/10.1177/2397847317696366 Shrader WA

This leads to the accumulation of free radicals and increased oxidative stress, which negatively impact skin health and freshness and reduce the bodys ability to efficiently detoxify