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Later research used fixed microgram amounts subcutaneously

Keshet R, Szlosarek P, Carracedo A, Erez A

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USA 89 , 98659869 (1992)

The synergistic action of cell wall proteins (such as Hwp1, Als3) and mannan can mediate the adhesion of fungi to host epithelial cells and extracellular matrix (Mayer et al., 2013), while the dynamic remodeling of -glucan and chitin supports hyphal extension and tissue penetration (Staniszewska, 2020)