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SIRT3 deficiency promotes lung fibrosis by augmenting alveolar epithelial cell mitochondrial DNA damage and apoptosis

This same principle applies to all peptide-based medications

Ishibashi K, Ishii K, Sugiyama G, Sumida T, Sugiura T, Kamata Y, Seki K, Fujinaga T, Kumamaru W, Kobayashi Y (2018) Deregulation of nicotinamide N-methyltransferase and gap junction protein alpha-1 causes metastasis in adenoid cystic carcinoma