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demonstrated that simvastatin alone significantly reduced bacterial load in Mtb-infected PBMCs via enhanced production of natural killer T cells, upregulation of co-stimulatory molecules in monocytes, increased the secretion of IL-1 and IL-12p70, and promotion of apoptosis and autophagy in monocytes (139)

2000;118(4):A414

and (2) they exert a broader influence by secreting a range of bioactive molecules, termed cachectic factors, which further propagate their effects (Fig

doi: 10.1186/s13075-020-02349-y 60 ZhangRMiaoJZhangKZhangBLuoXSunHet al

To model PD, 60 male C57BL/6 mice (1012 weeks old) were injected with MPTP and kept under pathogen-free conditions

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