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Phase I reactions involve the cytochrome P450 enzyme which is responsible for converting lipophilic (fat-loving) toxins into biotransformed intermediates that are more water-soluble

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Withdrawal: Remove needle at the same angle it entered

Changes in urine composition can therefore signal abnormalities in multiple organ systems

Abdalla, G.O

Clinical trials evaluated AOD-9604 for durations ranging from single doses to 24 weeks of continuous daily administration