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This is the first time the agency has taken steps to remove a currently marketed opioid pain medication from sale due to the public health consequences of abuse...[FDA Commissioner Scott Gottlieb, M.D.]: "We are facing an opioid epidemic a public health crisis, and we must take all necessary steps to reduce the scope of opioid misuse and abuse

The National Institute on Drug Abuse (NIDA) warns that individuals recovering from opioid addiction are at risk of relapse if exposed to these opioid-acetaminophen combinations

Melatonin is frequently used to improve sleep quality in children with ASD

*Correspondence: Su-Mei He, [email protected] Zhu, [email protected] Wei, [email protected] These authors have contributed equally to this work and share first authorship This article was submitted to Clinical Nutrition, a section of the journal Frontiers in Nutrition Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Some adverse reactions namely nausea and an unpleasant taste were reported

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