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This specific arrangement of aromatic and hydroxyl groups in phenols is responsible for the wide-ranging biological activities of phenols, including strong antioxidant potential, metal ion chelation, and free-radical scavenging (Figure 2).[29] The classification and sources of phenolics [30] Phenolic compounds form a very heterogeneous group of metabolites that are produced by plants and are classified according to the number of aromatic rings, the presence of hydroxyl groups, and the characteristics of the side chain

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To reconcile the discrepancy between the measurements and the solubility-based model predictions, previous studies have hypothesized that surface adsorption can be a predominant mechanism for water uptake of highly viscous SOMs (e.g., as characterized by particle rebound) 14,15

Many researchers combine both treatments, using minoxidil for immediate blood flow enhancement while GHK-Cu provides regenerative support