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Lysosomes are another subcellular compartment hypothesized to be involved in lipid peroxidation during the course of ferroptosis, supported by the fact that ferrostatins accumulate in lysosomes using stimulated Raman scattering (SRS) microscopy [35]

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50,51 The increased iron demand in these cells might explain their increased TFRC/CD71 expression, a feature they share with M-CLL cells