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Senescence is a state in which a cell permanently exits the cellcycle (no longer divides) in response to stress such as DNA damage, telomere shortening, oncogene activation, oxidative stress, or replicative exhaustion

Therapy-induced senescent cells can re-enter the cell cycle to show aggressive proliferative and cancer stem-like properties, presenting a risk for recurrence and treatment resistance

This product is not intended for human or animal use

Bacterial endotoxins, he says, can do a "serious number on you"

These dual manipulations of phospholipid metabolism provide Mtb with an escape from phosphate restriction specific to the infection of alveolar macrophages, one of the earliest steps in establishing pulmonary tuberculosis

10.3389/fnbeh.2017.00222 157 NirenbergM