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Supports appetite control during calorie deficits

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Correlation plots of gene expression in tumors were generated using the gplots R package (GSE22058, Fig 4B and D) or Excel (GSE14520, Fig EV5A and B)

Following sonication, samples were centrifuged at 800 g for 10 min at 4 C, and the supernatant (post-nuclear) was stored at 80 C

Glucose-6-phosphate dehydrogenase (G6PDH) activity Homogenized samples were pipetted into transparent 96-well plates (50 L/well) after dilution with assay buffer and pre-prepared standards for the G6PDH assay (cat