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glutathione transferase induction afatinib Decreased biosynthesis contributes to EGFR T790M-driven erlotinib resistance in non-small cell lung cancer Metabolic disposition of [14C]‐abivertinib, an
Metabolic disposition of [14C]abivertinib, an epidermal growth factor receptor tyrosine kinase inhibitor: Role of glutathione conjugation Wang 2021 British Journal of Clinical Pharmacology Wiley Online Library Glutathione Mediated Conjugation of Anticancer Drugs: An Overview of Reaction Mechanisms and Biological Significance for Drug Detoxification and Bioactivation Glutathione: Lights and Shadows in Cancer Patients PMC Glutathione transferases: substrates, inihibitors and pro drugs in cancer and neurodegenerative diseases Oncogenesis Glutathione S transferase Theta 2 causes drug resistance by inhibiting arsenic trioxide induced ferroptosis in pancreatic ductal adenocarcinoma ScienceDirect Establishment of Two In Vitro Glutathione Conjugation Models and Their Application in Covalent Drugs WuXi AppTec DMPK
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