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Conversely, the knockdown of Preso expression alleviated Ca 2+ overload and NO production [104,105,106,107]

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Indeed, substantial evidence has demonstrated that specific metabolic reprogramming directly regulates immune cell function, providing new perspectives and potential targets for the metabolic modulation of immune-mediated diseases

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Mice received 50 milligrams per kilogram of urolithin A daily (in food) for eight weeks, rats received 50 milligrams per milliliter (in water) for 24 hours following a simulated heart attack, and the older adults took 1 gram of urolithin A (via supplement) or a placebo daily for two to four months