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By contrast, drugs that target metabolic pathways (e.g., GLUT1 inhibitors, PPP inhibitors, PDK inhibitors, and glutaminase inhibitors) may provide promising efficacy in ovarian cancer cells harboring nutrient addiction

In doing so, they generate reactive oxygen species (ROS) as a by-product (Lee et al., 2010)

Similar clinical symptoms are found in individuals with hereditary IF deficiency (also called congenital pernicious anemia) in whom the lack of IF results in the defective absorption of vitamin B 12

Martin-McGill KJ, Bresnahan R, Levy RG, Cooper PN

isolated means that the material is removed from its original environment (e.g., the natural environment if it is naturally occurring)

This short-chain peptide is considered to help cell communication for a wide range of actions