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What the human evidence looks like How many human studies exist The 2025 systematic review by Vasireddi, Hahamyan, Salata, and colleagues in HSS Journal is the most rigorous available assessment of the BPC-157 literature (19932024) for orthopedic and sports medicine applications

Clinically manifested as progressive visual field defects and optic nerve damage, the selective and irreversible loss of retinal ganglion cells (RGCs), the central input neurons of the retina, forms the basis of glaucomatous pathology [320]

For example, it might be essential to reduce load initially and build tendon tolerance