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Assays were performed in 96 well microplates (clear polystyrene, flat-bottomed, Greiner bio-one), in a total volume of 200 L per well

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The nervous system withstands ageing better than other organs and systems (a phenomenon recognised long ago 516 ), which arguably reflects the high plastic potential allowing constant remodelling of the nervous tissue (the process which underlines life-long learning and adaptation) and high defensive and regenerative potential of neuroglia defining nervous system resilience and regeneration mending various insults accumulating during life-span

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99%

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( i-j ) FT282-CCNE1 cells ( i ) and Ovcar8-CCNE1 cells ( j ) were treated with olaparib alone or in combination with the IDH1i or mildronate

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Free radicals and ros induce protein denaturation by uv photostability assay

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BlGGT has also been reported to tolerate 4 M NaCl concentration without significant effect on its activity (Yang et al., 2011)

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