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An overflow of glutamate (the main endogenous excitatory amino in brain, at concentration of 515 mmol glutamate per kg body weight, higher than of any other neurotransmitter) is implicated in major psychiatric illnesses [1, 24,25,26]

The biosynthesis of carnitine depends on lysine and methionine, and requires a variety of vitamins and minerals as cofactors

Learn more in the update to our B Vitamins and Energy Drinks Review

Pons R, Darryl C: Primary and secondary carnitine deficiency syndromes

Collectively, Auger et al

Acetyl-L-carnitine improves cognitive functions in severe hepatic encephalopathy: a randomized and controlled clinical trial