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Tumor-associated macrophages: An effective player of the tumor microenvironment

To determine if pharmacological manipulation of autophagy effects SIPS, we treated GSH-depleted cells with the autophagic inducer rapamycin and autophagic inhibitors 3-MA and Baf-A1

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10.1016/j.tice.2021.101516 73

In vitro experiments showed that glabridin significantly inhibits Akt phosphorylation, suggesting it inhibits prostate cancer cell proliferation by regulating the PI3K/Akt pathway