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doi: 10.1016/j.chom.2018.10.019 50 Al AlamDDanopoulosSGrubbsBAliNATBMMacAogainMChotirmallSHet al

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Hence, we infer that this selectivity in favor of WD40 and against WD40 domain is not absolute but instead involves relative modulation of interaction affinity for one coatomer subunit versus the other through several interactions at the client-WD40 interface