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Gastrointestinal adverse events Very common (10% or more): Diarrhea (35%), abdominal pain (21%), vomiting (21%), nausea (12%) Common (1% to 10%): Constipation, dyspepsia, gastrointestinal disorder, melena Very rare (less than 0.01%): Abdominal cramps [Ref] Nervous system Very common (10% or more): Headache (37%), dizziness (18%), paresthesia (12%) Common (1% to 10%): Hypertonia, vertigo, taste perversion Frequency not reported : Seizures (with or without pre-existing seizure activity), increase in seizure frequency and/or severity [Ref] Metabolic Very common (10% or more): Hypercalcemia (15%), hypervolemia (12%) Common (1% to 10%): Anorexia, hyperkalemia [Ref] There are reports from clinical trials of significant hypertriglyceridemia associated with high doses of levocarnitine (3 g/day) given to uremic dialysis patients

Studies also suggest that bile acid derivatives such as UDCA may regulate bile acid metabolism and potentially reduce the risk of colon cancer

It supports energy production, improves endurance, and facilitates recovery after exercise

10.1007/BF03179070 284 ValgimigliL.AmoratiR

Chen HH., et al

The Vermeulen study found a clear divergence in therapeutic effects: Acetyl-L-Carnitine (ALCAR) had a statistically significant, targeted positive effect on mental fatigue and cognitive concentration , whereas Propionyl-L-Carnitine was more effective for general, physical fatigue