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They showed that VitC was able to target common metabolic aberrancies by decreasing adenosine triphosphate (ATP) and glucose transporter 1 (GLUT-1) levels, as well as by dissipating the mitochondrial membrane potential, which could sensitize KRAS mutant CRC cells to current treatments such as chemotherapy

[DOI] [PubMed] [Google Scholar] 72.Hsu C.C., Senussi N.H., Fertrin K.Y., Kowdley K.V

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2009;27(9):186372 Mountokalakis TD