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PMID: 40552401 Adv Sci (Weinh) AKT1 Phosphorylates FDX1 to Promote Cuproptosis Resistance in Triple-Negative Breast Cancer

Consistent with this mechanism of action, reduced levels of ATP-binding cassette (ABC) transporter A7 (ABCA7), which is encoded by the GWAS ABCA7 gene and mediates the efflux of cholesterol and phospholipids to form high-density lipoproteins, correspond to increased lipotoxicity ( SORL1 , another GWAS gene, encodes an apolipoprotein E receptor, which has also emerged from a combined lipidomic and proteomic study of Alzheimers disease (Xu et al., 2020)

Peptides are short chains of amino acids the same building blocks that make up proteins, just in shorter sequences (fewer than 50 amino acids)

Antioxidant Protection : Glutathione's primary function as an antioxidant makes it a powerful defense against the free radicals generated by environmental pollutants and UV exposure