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Most compounds that target tumor metabolism (methotrexate, 5-fluorouracil) fail to distinguish between tumor tissue and rapidly differentiating epithelial tissue (skin, bone marrow), 4,322 whereas therapies targeting the specific amino acid dependence of tumor cells are cell-selective, such as leukemic blasts that are selectively dependent on Asn, the use of bacterial-derived ASNase in pediatric ALL has significantly improved the cure rate

10.4161/cc.8.20.9701 55 HegiM.DiserensA.HamouM

presence of soot around the mouth, nose, or oropharynx

Xanthophylls are widely distributed in nature, with a group of compounds showing both chemical and physicochemical similarity

In terms of market development, Gotion Hi-Tech has recently received an order for power batteries from a subsidiary of Great Wall Motors

10.1016/j.ctim.2021.102769 18 LiuH.WeiP.KapplerJ