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HRW can improve the liver function of patients with hepatitis B by alleviating oxidative stress, alleviate non-alcoholic fatty liver disease in mice by antioxidant and anti-inflammatory effects, attenuate liver injury caused by obstructive jaundice, significantly reduce the incidence of hepatocarcinogenesis, reduce the maximum tumor volume, and also have protective effects on encephalopathy, liver ischemia reperfusion and liver resection injury 17,18,19,20,21,22

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The predicted PD overlaid well with the observed PD data measured in tumor tissue extracted on day 42, after the last dose of continuous daily treatment (Fig

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