Immunomodulatory effect of Bifidobacterium breve on experimental allergic rhinitis in BALB/c mice
77 Fukudas team found that 9 of the 13 differentially expressed genes in allergic patients were mitochondria-related genes, including those producing cytochrome oxidases II and III, and NADH dehydrogenase
No significant difference in UPDRS scores was observed between the hydrogen group and the placebo group
However, the corresponding translated protein level and the enzymes catalytic activity are significantly lowest because the AMR1L1 protein binds to the GMP enzyme and promotes its hydrolysis via ubiquitination-dependent degradation through the 26S proteasome pathway, thus controlling AsA biosynthesis at the post-translational level (Ma et al., 2022)
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