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An experimental investigation found that -carotenoids protect against skin photo-related illnesses by scavenging excited triplet forms of endogenous photosensitizers in patient blood and skin, including protoporphyrin, a hereditary erythropoietic protoporphyria [153]

Next, we analyzed the conserved sequences of XIST promoters from human genomes in the JASPAR database, and two conserved sequences were identified within the 2000 bp upstream from the transcription start site

Multifaceted mitochondria: moving mitochondrial science beyond function and dysfunction

However, very high intakes of PEITC or BITC (25 to 250 times higher than average human dietary isothiocyanate intakes) have been found to promote bladder cancer in rats when given after cancer initiation by a chemical carcinogen (70)

Available at: (Accessed on 19th December 2025)

Ferritin-targeted strategies remain largely underexplored in brain cancers and could represent a novel approach to induce ferroptosis in embryonic-origin tumors, such as glioblastoma (GBM) and medulloblastoma (MB), potentially sensitizing CSCs to conventional therapies by reducing their antioxidant capacity