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The associations between smoking, physical inactivity, obesity, and Asthma severity in the general US population

COXs are abundantly expressed in neurons and microglia across various animal species ( in vivo and in vitro experimental showed that tumor necrosis factor- (TNF-)-mediated BBB breakdown is linked to COXs up-regulation the expression and activity of matrix metalloproteinases (MMPs) (Sugimoto et al., 2009)