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Derebail Nature Reviews Nephrology.2022

Lab markers for glutathione: Free Glutathione (GSH), Glutathione disulphide (GSSG) and GSH/GSSG ratio

Specifically, -KG functions as an epigenetic cofactor to maintain TET-dependent transcription of RBP YBX1, which binds to the 5UTR of human PRKAA1 mRNA to ensure efficient AMPK1 translation