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4.4 PPARs and NF-B signaling pathways PPARs are ligand-activated transcription factors belonging to the nuclear hormone receptor superfamily and are key regulators of various pathophysiological processes related to energy metabolism, including lipid, carbohydrate metabolism, and inflammation

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Boosted metabolism : Helps digest fats, proteins, and carbohydrates more effectively

Abstract The co-inhibitory immune checkpoint interaction between programmed cell death-protein 1 (PD-1) and programmed cell death-ligand 1 (PD-L1) serves to regulate T-cell activation, promoting self-tolerance