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Autosomal-dominant polycystic kidney disease (ADPKD): Executive summary from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

Further, current data identified a cross-connection between altered Hcy levels and ocular diseases such as retinopathy, cataract, maculopathy, optic atrophy, pseudo-exfoliative glaucoma, and retinal vessel atherosclerosis [179]

PMID: 14636871

Indeed, L -2HG is considered more potent than D -2HG, with both enantiomers recognized as antagonists of mammalian cellular function and potent oncometabolites

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